ncRNA name | hsa-miR-146a |
ncRNA Category | miRNA |
Disease name | Graves ophthalmopathy |
Species | Homo sapiens |
Tissues/Cell_line | serum |
Methods | qRT-PCR |
Expression pattern | down-regulated |
Functional description | Active-GO and inactive-GO group had significantly lower miR-146a expressions than control. Active-GO group had significantly lower miR-146a than inactive-GO group. Serum levels of IL-17 and miR-146a were both significantly correlated with clinical activity score (CAS) in GO patients. There was a significant negative correlation of circulating miR-146a expression with serum IL-17 levels (P < 0.01). |
PubMed ID | 25100151 |
Year | 2014 |
Title | Circulating levels of miR-146a and IL-17 are significantly correlated with the clinical activity of Graves' ophthalmopathy. |
Drug-related ncRNA | NO |
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